RWE Lead Scientist Bone

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Date: May 25, 2019

Location: Anderlecht, Brussels, BE

Real World Evidence, Lead Scientist (Bone)


Location: Brussels, Belgium or Slough, UK

At UCB, we believe that one day, Real-World Data (RWD) will be the most influential source of evidence in healthcare, ensuring every patient gets access to the right care. The Global RWE Practice strives to harness the full potential real-world data to support UCB’s mission to enhance our understanding of disease and the real-life experiences of patients so that UCB can deliver the right drug and the right care to the right patient. Will you join us in our pioneering adventure?

We are looking to fill the position of Real-World Evidence (RWE) Lead Scientist for Bone, to support the business unit as well as our preparations for the anticipated launch of romosozumab (EVENITY™), humanized monoclonal antibody that binds to and inhibits sclerostin, a protein secreted by osteocytes in the bone that is a pivotal regulator of bone formation. Romosozumab has a dual effect of stimulating bone formation and reducing bone resorption, thereby reducing the risk of fractures in patients living with osteoporosis.

The position will be ideally based in one of our primary European global locations (Brussels, Belgium; Slough, UK).

As a Lead RWE Scientist, you will be responsible for designing and executing global real-world evidence (RWE) projects using real-world data (RWD) to:

  • contribute to our understanding of the natural course of osteoporosis and other fracture-related conditions, treatments and patient outcomes
  • drive strategic internal decision-making towards the development of clinically differentiated solutions that address unmet medical needs
  • support external decision making by key stakeholder groups such as policy makers, payers, and prescribers
  • contribute to the wider medical understanding of bone-related diseases
  • guide clinical development decisions with regards to the selection of appropriate clinical/patient-relevant endpoints, treatment comparators, target patients segments.
  • support key components of UCB’s patient value strategy through the exploration of new perspectives that can augment ‘traditional’ clinical data, thereby driving emerging opportunities designed to reduce the time to patient access to new medicines.

Furthermore, as a Lead RWE Scientist you will contribute by:

  • co-creating Global RWE Strategy, tactical & communication plans with the RWE Strategy Lead for Bone
  • leading RWE study execution, including study design and analysis specification and protocol development
  • liaising with RWE methodologists and RWD specialist regarding study design and choice of data source respectively
  • managing a dedicated group of RWE contract scientists, currently three, and overseeing their execution of systematic and pragmatic literature reviews, analytical projects, and report creation
  • providing RWE analysts with clarifications concerning protocol implementation
  • driving interpretation of analysis in collaboration with RWE Strategy Lead & other relevant internal stakeholders, and communicating analysis interpretation internally and externally managing internal & external communication including scientific publications
  • maintaining an external network of collaborators to support realization of RWE strategic plan

Finally, as part of the Global RWE Practice, you will have the opportunity to support the continued growth of the team who is accountable for all global RWE activities undertaken at UCB.

Interested? For this position, you’ll need the following education, experience and skills:

  • Minimally required experience: 5 years successfully delivering global and/or local RWE projects from conceptualization to publication within the pharmaceutical industry or with a recognized expert consultancy; demonstrable publication record in relevant peer-reviewed scientific and/or clinical journals   
  • Desirable/preferred experience: as above; depth and breadth of experience will be reflected in the grade.


Technical Expertise/Skills

  • Training in the areas of epidemiology, pharmacoepidemiology, outcomes research, health economics, biostatistics, data science or related fields
  • Good background knowledge of industry trends and best practices, specifically related to epidemiology/outcomes research
  • Good knowledge and understanding of applicable regulations in pharmacovigilance and clinical development
  • Ability to solve scientific and technical questions/problems related to the epidemiology and pharmacovigilance environment
  • Expertise in the EU5/ US healthcare environment (and changes therein)
  • Ability to leverage changes in healthcare systems to help plan and drive development of innovative patient access solutions in support of UCB compounds, resulting in value for institutional/individual stakeholders in addition to patients and physicians



  • Excellent and effective oral/written skills in English
  • Proven ability to write/edit scientific communications (abstracts, poster presentations, podium presentations, manuscripts, etc.)
  • Ability to deliver presentations to senior management or industry audiences with a relaxed and proficient presentation style



  • Develops and maintains strong collaborative relationships with key partners and stakeholders
  • Demonstrates successful collaboration with multidisciplinary cross functional and cross-cultural project teams
  • Proactively uses his/her relationships with internal and external stakeholder groups to synthesize thinking, build advocacy and empower implementation of the solutions in support of UCB portfolio performance and patient outcome
  • Is a driver for innovation and creativity
  • Demonstrates visionary, strategic and tactical capabilities

Job Segment: Epidemiology, Scientific, Medical, Public Health, Scientist, Engineering, Healthcare, Science

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