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Let's push the boundaries together and make the most of your talents!

Research Associate - Cell Line Generation


Boston, Massachusetts, United States

Job Function:  Research & Early Development
Job ID:  65234

Help us transform patients' lives.

At UCB, we put our heart, soul and skills into making a difference for people living with severe diseases.  Working together to push the boundaries, we blend the best of our talents to unlock innovation. Will you join us in this pioneering adventure? 


To strengthen our Early Research and Development Team, based in our Boston office in Bedford, MA, we are looking for a talented individual to fill the position of: Research Associate.


You like to work in an environment where you can:


Job Summary  

For our Bedford laboratory, we are seeking a highly-motivated full-time Research Associate to perform a variety of complex technical duties involving mammalian cell engineering for signal transduction and reporter assay development.

The successful candidate will be responsible for transgene design, generating a variety of disease relevant cell culture models, designing and executing experiments to test engineered cell lines, analyzing data, and communicating results to UCB colleagues. The successful candidate will have the opportunity to learn cutting-edge genomic technologies while contributing to ongoing drug discovery and development efforts across UCB sites.


Major Accountabilities

  • Generation of cellular models to mimic disease biology and serve as functional screening tools by CRISPR-based approaches and other transgene delivery methods
  • Develop work-plans with international UCB colleagues to deliver timely solutions to cell model needs in UCB therapeutic areas
  • Plan, execute and troubleshoot routine assays and procedures (i.e. molecular cloning, PCR, transfections, transductions, cell-based reporter assays, etc.)
  • Accountability for achieving project milestones and delivering on objectives


Essential Requirements

  • BS in biological sciences or related field
  • 1-3 years of relevant laboratory experience, in academic, pharmaceutical or biotechnology settings.
  • Proficiency in basic molecular biology including cloning, PCR, mammalian cell culture, transfection procedures and immunoassays (e.g. flow cytometry, ELISA, Western blotting)


Desirable Requirements

  • MS preferred
  • Experience in using functional genomics tools including CRISPR/Cas9 gene editing preferred
  • Experience with lentivirus generation and transduction to generate stable cell lines preferred
  • Ability to work as part of a team as well as independently
  • Ability to learn and implement new assays with high accuracy and precision
  • Ability to teach and transfer skills (e.g. cell culture, reporter assays, screening technologies) to less experienced personnel



About Us

At UCB, we come together every day to work, laser-focused, on a simple question: How will this create value for people living with severe diseases? By putting patients at the heart of everything we do, our approach – from discovery to development to delivery – is continuously transformed and designed around patient needs and their journey.

With a team of approximately 7,500 employees worldwide operations in more than 40 countries, we are a global biopharmaceutical company investing more than a quarter of our revenue in cutting-edge scientific research. We are focused on addressing chronic, neurological, immunological, and bone diseases. We are looking for people with passion and empathy who develop a real understanding of patient’s needs and can deliver thoughtful solutions to decisionmakers across the heath care ecosystem.

Curious to know more? Please visit our website www.ucb.com.


UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

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