Gene Editing Biologist in Neuroinflammation

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Date: Jul 11, 2019

Location: Braine L'alleud, Walloon Brabant, BE


Gene Editing Biologist in Neuroinflammation


Job Location: Braine L’Alleud, Belgium (some travel primarily to US and UK required)

Hiring level: Position/Title and compensation commensurate with experience


At UCB everything we do starts with a simple question: “How will this make a difference to the lives of people living with severe diseases?” We do that by connecting our ground-breaking science with patients and their families around the world living with the physical and social burdens of autoimmune and neurological disorders. Those connections offer new perspectives, drive innovation, and offer the hope of a new generation of therapies that will help improve lives on a global scale.


Role Overview                                   

This is an exciting role for a talented gene editing/stem cell biologist to work with the neuroinflammation team on identification and validation of novel drug targets, and enable their progression through the preclinical pipeline. The ideal candidate will report to the head of neuroinflammation and will drive the conceptual and experimental execution of gene editing/ target validation activities working together with our iPSC sub-team.  He/She will need to align with key internal stakeholders across UCB’s research sites to define experimental approaches, specific studies, and priorities. He/she will interface with the functional genomics group in Durham, NC and a world-class network of external collaborators to enable transfer and integration of cutting-edge technologies into our target identification and cross-validation toolbox.


Technical Capabilities

  • Hands-on expertise with gene editing tools and other cellular and molecular biology technologies backed by a strong publication record is required.
  •  Experience with genetic modification of iPSC-derived neurons and microglia/glia is highly desirable.
  • Experience with high-throughput functional genomics screens and high-content imaging is highly desirable.
  • Experience with next generation, single-cell and epigenetic sequencing technologies highly desired.
  • In vivo gene editing in rodents and experience with animal models of neurodegeneration highly desirable.


Professional and Personal Attributes

  • Strong inter-personal and communication skills, ability to work in a matrix organization
  • A can-do attitude and exceptional attention to detail
  • Self-starter, dynamic, independent and innovative
  • Open-minded and flexible to work in a fast-paced environment
  • Potential to grow into the role of pre-clinical project team leader


Additional Requirements:

Ph.D. in Molecular biology

Genetics or Stem Cell Biology

Spoken and written English proficiency is required

French proficiency is desirable


We can offer you an informal and open working environment that does not lock scientists into structure and hierarchy.  Freedom to take space to pursue your own ideas and make a difference.  Opportunity to gain internal and external visibility through interactions with other UCB teams and with world-renown academic investigators. Opportunity to grow both as a drug hunter and leader through participation in project teams and our career/personal development programs.


Job Segment: Genetics, Medical Technologist, Neurology, Biologist, Molecular Biology, Healthcare, Science

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