Intravital microglia imaging Scientist-Neuroinflammation

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Date: Feb 16, 2019

Location: Braine L'alleud, Walloon Brabant, BE

UCB aspires to be the patient-centric global biopharmaceutical leader transforming the lives of people

living with severe diseases. We focus on central nervous system and immunology disorders. Our promise

is to help tackle the serious unmet medical needs affecting patients around the world. We now have an

exciting opportunity in New Medicines (our research organization) at our site in Braine L’Alleud (close to

Brussels, Belgium), within the Neurosciences group, for a (m/f)



Intravital microglia imaging Scientist-Neuroinflammation



Job nature and scope:


Tis is an exciting role for a talented intravital imaging microglia biologist (Ph.D.) to work with the neuroinflammation

team and engage in breakthrough research in a vibrant drug discovery environment – inspired by patients, driven by

science. The individual will be involved in cutting edge neuroimmunology research including validation of novel drug

targets and supporting their progression through the preclinical project pipeline. The neuroinflammation team works

in a matrix organization, closely collaborating with other teams in the neuroscience and immunology therapeutic areas

and with external parties (contract research organizations and academic collaborators), therefore the ideal candidate

will also act as a representative of the neuroinflammation to UCB project teams and academic collaborations.



Education, experience and skills:


Professional and Personal skills:


  •  Potential to grow into the role of pre-clinical project team leader
  •  Excellent communication and scientific writing skills
  •  Self-starter, dynamic, independent and innovative
  •  Open-minded and flexible to work in a fast-paced environment
  •  Able to challenge and improve the efficiency of our way of work
  •  Focused and well organized
  •  Exceptional attention to detail



Technical Skills:


  •  In depth knowledge of microglial biologies in the context of synaptic architecture maintenance  in neurodegenerative disease, backed by publications.
  •  Experience with deep immune phenotyping, ex vivo flow cytometry and cell sorting technologies highly desirable.
  •  Hands-on experience with in vitro and intra-vital imaging of microglial-neuronal/synaptic interactions is required.
  •  Experience with in vivo labeling and imaging using calcium indicator dyes and other fluorescent reporters is required.
  •  Certifications for work with animals are required.
  •  Knowledge of animal models of neurodegeneration highly desirable.

Job Segment: Medical Technologist, Neurology, Scientific, Immunology, Medical, Engineering, Healthcare

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