Microglia/Stem Cell Biologist-Neuroinflammation

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Date: Nov 13, 2018

Location: Braine L'alleud, Walloon Brabant, BE

UCB aspires to be the patient-centric global biopharmaceutical leader transforming the lives of people living with severe diseases.

We focus on central nervous system and immunology disorders. Our promise is to help tackle the serious unmet medical needs

affecting patients around the world. We now have an exciting opportunity in New Medicines (our research organization) at our site in

Braine L’Alleud (close to Brussels, Belgium), within the Neurosciences group, for a (m/f)



Microglia/Stem Cell Biologist-Neuroinflammation



Job nature and scope


This is an exciting role for a talented microglia/stem cell biologist (Ph.D.) to work with the neuroinflammation team and engage in breakthrough

research in a vibrant drug discovery environment – inspired by patients, driven by science. The ideal candidate will be involved in cutting edge

drug discovery research, including validation of novel drug targets and supporting their progression through the preclinical project pipeline. The

neuroinflammation team works in a matrix organization, closely collaborating with teams in the neuroscience and immunology therapeutic areas

as well as external parties (contract research organizations and academic collaborators), therefore the ideal candidate is expected to act as a

representative of neuroinflammation to UCB and academic project teams.



Education, experience and skills


Professional and Personal skills:


  •  Potential to grow into the role of pre-clinical project team leader
  •  Excellent communication and scientific writing skills
  •  Self-starter, dynamic, independent and innovative
  •  Open-minded and flexible to work in a fast-paced environment
  •  Able to challenge and improve the efficiency of our way of work
  •  Focused and well organized
  •  Exceptional attention to detail


Technical Skills:


  •  A background in molecular biology/glial stem cell biology or neuroinflammation is required.
  •  Hands-on experience with human primary IPSC-derived microglia and brain organoids is required.
  •  Experience with genetic manipulation (AAV and CRISPR/CAS9 ) of IPSC-derived glial cells or glial cell lines is required.
  •  Experience in setting up pathway activation detection methods paired with high-content imaging or flow cytometry readouts is required.
  •  Transcriptome profiling and molecular pathway analysis highly desirable.

Job Segment: Genetics, Medical Technologist, Neurology, Cell Biology, Molecular Biology, Healthcare, Science

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