Clinical scientist Translational Medicine Neuroscience

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Date: May 15, 2019

Location: Braine L'alleud, Walloon Brabant, BE

UCB has a strong market presence in more than 40 countries, € 3.88 billion in revenue (2015), 7,500 employees and numerous strategic partnerships across the industry. It is Headquartered in Brussels, Belgium.

UCB is a patient-centric global biopharmaceutical leader transforming the lives of people living with severe diseases. This strategy involves focusing on severe diseases in three therapeutic areas: Central Nervous System and Immunology as well as Bone disease. UCB also has a selective presence in primary care. As severe diseases are treated by a relatively  small  number  of specialists, UCB has a close relationship and regular dialogue with physicians and their patients - an essential ingredient for understanding and addressing the daily physical and social symptoms of these diseases. Severe diseases also require a smaller sales force, so more resources can be devoted to R&D and other functions. 


   Within the New Medicine Patient value Unit located in Braine L’Alleud close to Brussels, we are now looking for a (m/f)



Clinical scientist Translational Medicine Neuroscience




Job nature and scope


The complexities of severe diseases are beyond the expertise and resources of a single organization. That is why UCB has teamed up with partners. From research and development to marketing and supply chain, it has joined forces with organizations such as Amgen (R&D), Sanofi (Marketing - antihistamine) and Lonza (Manufacturing. Networking resources and expertise not only results in cost reductions but also to cross-fertilize the knowledge and skills of the staff across the world, as well exploit opportunities to develop therapies around the clock, across time zones. This is supported by an entrepreneurial, empowered and results-driven culture and a relentless commitment to the highest standards of quality. Currently there are 9 molecules in development across multiple indications in immunology and CNS at this time.

Reporting to the Head of Early Clinical Neurology, this position is supporting actively the clinical strategy of the Neurology portfolio from early translation including first-in-man studies, the design and execution of proof of concept studies and translational medicine and biomarker strategy for the Neurology Early Development pipeline. The applicant is expected to be a clinical expert in neurology with a strong track record of delivery in industry. He or she will work closely with colleagues in the Neurology Therapeutic Area, Global Exploratory Development and the Neurology Patient Value Unit to deliver a portfolio in line with the UCB Patient Value strategy. He will provide leadership in Clinical programs, lead through influence across the cross- functional matrix and establish him-/herself as a respected clinical and drug development expert within UCB.

The role holder will work with the Research Project Leaders to generate a portfolio of Phase 0 projects to support the pipeline with a focus on generating patient stratification hypotheses and identifying biomarkers for target engagement and patient selection. These studies will generally be delivered through a network of academic translational medicine sites and will be executed with the support of GED functions.



Major accountabilities


  • Actively supports the growth of the Early Clinical Neurology group so that it can provide Clinical Therapeutic expertise to the Discovery and Early Development Portfolio
  • Develop strong working relationships with the Research Project Leaders, The Clinical Project leaders, with reach into Med Practice and nPVU missions.
  • Be a core member of PST and leading CRSTs.
  • Build a phase 0 portfolio of projects in support of the Pre DP4 and Early Development pipeline focusing on patient stratification hypotheses and target engagement and patient selection biomarkers.
  • Provide clinical leadership for Neurology assets



Education , Experience and Skills:


  • Neurologist/Psychiatrist (or experienced Neuroscientist) with early development experience in the pharmaceutical industry. Board certification or similar clinical experience in Neurology/ Psychiatry or an equivalent neuroscience training.
  • Has experience in (preferably early) clinical development in the pharmaceutical industry, with track record of delivery in Neurology as demonstrated by strong publication record.
  • Track record in translational medicine and exploratory trials, with a focus on moving concepts/compounds from discovery research to PoC.
  • Experience in implementation or different biomarker modalities in early clinical development.
  • Disease area expertise in Neurodegeneration PD (preferred) and/or PSP, AD
  • Extensive Global Network in Neurology and global drug development experience
  • MD with extensive experience in Neurology early development and translational medicine
  • Strong communication skills with good presentation skills
  • High performer, strong team-commitment, innovative and can manage uncertainty
  • Ability to work independently and to solve complex problems and multiple projects in supervisory capacity
  • Listening, coaching, mentoring, facilitation, influencing and negotiation skills
  • A participative management style with the ability to build effective team relationships with colleagues at all levels in the organization

Job Segment: Clinic, Neurology, Scientific, Medical Technologist, Immunology, Healthcare, Engineering

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