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Post-doctoral researcher in epilepsy


Braine L'alleud, Walloon Brabant, Belgium

Job Function:  Research & Early Development
Job ID:  63705

UCB aspires to be the patient-centric global biopharmaceutical leader transforming the lives of people living with severe diseases. Our promise is to help tackle the serious unmet medical needs affecting patients around the globe. An important part of our philosophy is to take a holistic approach to patients, which aims to find solutions tailored to their circumstances. By taking into account patients’ individual characteristics and lifestyles, such as age, diet, family history and genetic profile, we are also coming closer to providing personalized therapies. The company’s international R&D organization is New Medicines responsible from early research up to clinical Proof of Concept and focused on two main Therapeutic Areas, Immunology and Neurology. Immunology is based in Slough UK, while Neurology is based in Braine-l’Alleud, Belgium, close to the company Headquarters located in Brussels. UCB New Medicines is recruiting within Neuroscience Discovery Biology for the site in Braine-L’Alleud a (m/f):

Post-doc Scientist in Epilepsy

Post-doctoral researcher in epilepsy, Neuroscience Discovery Biology

To strengthen our research investment to identify novel drugs to cure refractory epilepsy, we are currently hiring a talented PhD for a 3-year post-doctoral research position to join Neuroscience Discovery Biology group based in Braine L’Alleud, Belgium. The aim is to understand underlying mechanisms of mToropathies in drug resistant epilepsy. Identification and validation of new pathways and potential drug targets in hiPSC-derived neurons is the major aim of the research. This will require the development of new technologies and assays with various molecular and cellular approaches.

In order to achieve this goal, we are seeking a highly skilled post-doctoral researcher with neuroscience background, ideally with expertise in the epilepsy field.  The position allows working in a multi-disciplinary and collaborative environment.

Experience &Technical Skills

The candidate has very good knowledge and experimental skills in molecular and cellular biology, particularly human iPSC culture and neuronal differentiation, viral transduction, CRISPR gene editing, neuronal phenotyping. Experience in either electrophysiology (MEA), high content imaging, transcriptomics, Turbo-ID or MS are additional assets. She/He is skilled in designing well thought experimental studies and has the appropriate analytical skills to quantify and analyze data using Excel, Graphpad Prism and other statistical software. She/He is proactive in challenging current models/theories by proposing constructive new ideas.

The position requires following:

  • Engage in exciting new drug discovery research for identification of new targets involved in epilepsy
  • Develop critical assays for target identification and validation
  • Perform target validation and mechanism of action studies
  • Knowledge and experience of a wider range of in-vitro biological techniques, which may include molecular biology (CRISPR), biochemistry, analysis of signaling pathways, immunocytochemistry
  • Knowledge on primary cell culture, iPSC differentiation methods

Education & Soft skills

The ideal candidate will have his/her PhD in the field of neuroscience and will have a proven track record of publications in peer reviewed, high quality scientific journals.

  • PhD in Neuroscience
  • Expertise in neurobiology
  • English required
  • Strong analytical skills
  • Focused and well organized
  • Inspirational and outstanding scientist with an innovative and entrepreneurial spirit
  • Dynamic and passionate about science 
  • A team player and a good networker
  • Open and honest with strong, constructive communication and negotiation skills
  • Coach and train scientific staff in the use of new technologies
  • Represent and promote UCB research activities at internal and external scientific meetings and by publishing studies in peer reviewed journals
  • Develop a strong network with academic experts and initiate and run external studies and collaborations
  • Work proactively across sites and functions and with external parties

To apply please go to www.ucb.com/careers .

Discover more about the remarkable UCB Talent Blends and how you can contribute to the mix at www.ucb.com/careers .

Job Segment: Biochemistry, Genetics, Neurology, Immunology, Medical, Healthcare, Science

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