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Process Engineer


Braine L'alleud, Walloon Brabant, Belgium

Job Function:  Process & Technology Development
Job ID:  65279

Process Engineer

Pharma Sciences

Braine L'alleud - Belgium


An exciting opportunity has arisen in Chemical Process R&D (Small Molecule world).  As a member of the Engineering Sciences group, you will use your chemical/process engineering knowledge and expertise to contribute to the development and scale-up activities for one or more pipeline programs for the department. 


This is a highly practical role where you will be working primarily in the R&D laboratories (for small molecule process development) to build technology and process understanding. As the projects advance through development, plant support will also be required across scales, culminating in the transfer of projects and technologies to the commercial manufacturing facilities.


The role is fast-paced and dynamic as you will be working in a number of project teams. You will thrive in this environment if you are able to effectively manage multiple priorities, communicate your recommendations clearly and enjoy working in teams.


Key job responsibilities:

•            Deliver process engineering support to development projects as part of a development project team;

•            Conceive, plan, execute and manage scale-up activities, both internally and at partners;

•            Deliver process models, which demonstrate optimized engineering configuration of plant and maximize process potential;

•            Effectively contribute to the development of end-to-end process understanding and control of the manufacturing process, by integrating broad knowledge of each unit operation.

•            Ensure detailed and comprehensive documentation of all relevant activities to comply with regulatory requirements or to ensure complete capture of program and process knowledge.


Basic qualifications:

•            BSc, M.Sc. or equivalent in chemical/process engineering with relevant industrial experience in pharmaceuticals / fine chemicals or any process applications.

•            A proven track record in at least three of the following technical areas: process development of pharmaceutical unit operation batch and/or continuous (e.g. reaction, distillation, crystallisation, filtration and drying), process industrialisation and scale-up, process simulation (unit ops, kinetic and thermodynamic), process control, and application of process analytical technologies (PAT).


Preferred qualifications:

•            Demonstrated hands-on and practical ability in process development with experience in the application of state-of-the-art engineering equipment or relevant PhD;

•            Some practical working experience of key software for process design and scale-up (e.g. Dynochem, Aspen, Visimix and / or CFD) or other software for mathematical model implementation and development e.g. MatLab, gProms;

•            Relevant exposure to Statistical Modeling (DoE) or Multivariate Analysis (Chemometrics) software packages;

•            Analytical techniques for  process monitoring e.g. FBRM, NIR, PVM, HPLC, GC, KF;

•            Knowledge of current regulatory requirements and expectations applicable to the pharma industry, and prior experience working in a cGMP environment.

•            Ability to handle several projects in different stages of development at the same time, using initiative and imagination to meet agreed objectives and timelines;

•            Some proficiency in both English and French languages would be advantageous.

•            Effective interpersonal, organizational and communication skills for working in a multi-disciplinary scientific team environment;

Job Segment: Process Engineer, Manufacturing Engineer, Engineer, Chemical Research, Supply, Engineering, Operations

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