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Let's push the boundaries together and make the most of your talents!

Senior Process Engineer

Location: 

Braine L'alleud, Walloon Brabant, Belgium

Job Function:  Process & Technology Development
Job ID:  68268

Help us transform patients' lives.

At UCB, we put our heart, soul, and skills into making a difference for people living with severe disease. Working together to push the boundaries, we blend the best of our talents to unlock innovation.  Will you join us in our pioneering adventure?

To strengthen our Biologics Pilot Plant team, we are looking for a talented individual to fill the position of: Senior Process Engineer for our Belgian site, in Braine-L’Alleud.

 

As a Senior Process Engineer, you will identify and foster purposeful partnerships with key scientific influencers to drive new sources of patient value.

You like to work in an environment where you can:

  • Support the manufacturing activities in Braine site and in UCB’s manufacturing partners facilities.
  • Be a pillar of biologics purification areas including mixing, chromatography, viral clearance, ultrafiltration / diafiltration, filtration and formulation.
  • Support the industrialization of early & late stage UCB biologics and impact the development of UCB’s pipeline of biotech processes.

 

The Biologics Pilot Plant in Braine-l’Alleud is a multiproduct facility, manufacturing biological Drug Substance for human use, with several different products / manufacturing campaigns per year.

 

You will contribute by:

 

  • Leading / contributing to the transfer of purification processes from small-scale development units to the Pilot Plant and from Pilot Plant to the commercial manufacturing sites.
  • Building and maintaining an effective network across Manufacturing sciences / Biologics Pilot Plant, Process Development, support teams, Quality Assurance, Analytical, suppliers and Global Regulatory Sciences groups.
  • Providing technical expertise & leadership for the investigations and resolution of downstream process deviations in large scale cell culture processes through effective root cause analysis, Impact assessment, CAPA definition (& execution) and design of (pilot / scale down) studies. The role includes authoring change controls for new process introduction or to assess technical modifications.
  • Leading the design & troubleshooting, de-risking activities faced during the execution / introduction of the process in compliance with cGMP rules.
  • Driving / supporting continuous improvements of equipment, systems and methods to increase UCB’s Biologics Pilot Plant efficiency.
  • Initiating design of new – or modified process equipment and supporting (re-) qualification of equipment, (re-) validation.
  • Understanding and writing downstream process automation recipes (e.g. Unicorn).
  • Providing subject matter expertise, representing the Downstream function at the Biologics Pilot Plant, during regulatory inspections and queries from health authorities.
  • Demonstrating a strong knowledge of cGMP compliance

 

Interested? For this position you’ll need the following education, experience and skills:

 

  • PhD, MSc or BSc level of education in process or bioprocess engineering or biotechnology related fields with at least 5 years of experience in downstream process development or manufacturing sciences in the biopharmaceutical industry.
  • Strong knowledge of technologies and unit operations involved in downstream bioprocessing working with biologics.
  • Practical experience with technology transfers, scale-up and optimization of processes.
  • Track record of defining / leading / coordinating specific projects.
  • Continuous improvement mindset and experience with lean manufacturing methodologies.
  • Experience of equipment qualification / validation, including URS creation and qualification execution.
  • Excellent oral & writing skills, both in French & English, to author and approve comprehensive and accurate technology and manufacturing documentation, procedures, specifications and protocols / reports.
  • Ability to compile, analyze and summarize large amounts of information and complex situations into a comprehensive but concise document that efficiently supports decision making processes.

 

 

Why you should apply

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees – just as we do for the patients we serve.

 

If you believe you are the perfect match to join us on our pioneering adventure, then we invite you to apply and tell us more about your profile and motivation.

 

About us.

UCB- Inspired by Patients. Driven by Science. Everything we do starts with a simple question: “How will this create value for people living with severe diseases?” By putting patients at the heart of what we do, our approach – from discovery to development to delivery – is continuously transformed and designed around patient needs and their journey.

With a team of approximately 7,500 employees and operations in more than 40 countries, we are a global biopharmaceutical company investing more than a quarter of our revenue in cutting-edge scientific research. We are focused on addressing chronic, neurological, immunological, and bone diseases.

Curious to know more? Please visit our website www.ucb.com.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. 

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