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Mammalian Cell Culture Scientist


Slough, Berkshire, United Kingdom

Job Function:  Research & Early Development
Job ID:  69297

Cell Culture Scientist


To strengthen our Upstream Process Sciences department, based in our UK head office in Slough, we are looking for a talented individual to fill the position of: Cell Culture Scientist.  

As a Cell Culture Scientist, you will be involved in clone selection support, process optimisation studies, process troubleshooting investigations, evaluation of cellular responses to process operations, assessment of effects on product quality, determination of process scalability and tech transfer to GMP facilities.  

You like to work in an environment where you can:

  • Collaborate with various process scientists (upstream and downstream) and analytical scientists as well as research and clinical manufacturing groups.
  • Utilize knowledge in cell culture process development, biochemical engineering, statistics, molecular biology, analytical methods and cellular metabolism to aid in process development and optimization of upstream processes producing protein therapeutics for projects at the early stage of clinical development.


You will contribute by:

  • Performing cell culture process development experiments for the development of new manufacturing processes and the improvement of existing processes at lab and pilot scale.
  • Trending and analysing laboratory data and present results to line manager, USP team and at internal meetings.
  • Providing traceable records of lab work, experimental design and report writing.
  • Representing the Upstream Process Sciences group in cross-functional project teams.
  • Aiding with reviewing, writing and updating internal procedures and documents.
  • Contributing to the maintenance and housekeeping of a safe laboratory working environment, including contribution to writing and reviewing HSE risk assessments related to USP activities.
  • Providing technical expertise in upstream processing for internal customers (e.g.  New Meds, DSP, Analytical Sciences Biologicals, QA, RA, Bio CMO Management).


Interested? For this position you’ll need the following education, experience and skills:

  • Demonstrated expertise in the operation of lab and pilot scale cell culture processes, including the use of various bioreactor systems, relevant operating control software and excellent aseptic technique.
  • Ability to design and perform process development experiments as well as excellent data interpretation, drawing of conclusions and proposals for further work.
  • Ability to learn and use appropriate data management concepts and tools.
  • Ability to author comprehensive and accurate SOPs and protocols/reports.
  • Experience with high throughput technologies, automation, miniaturisation, statistics and/or programming is preferred.
  • Experience in cGMP and large-scale manufacturing equipment and practices and with the transfer of technology to cGMP operations is preferred.
  • Having a sound understanding of CHO physiology is preferred.


Why you should apply

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees – just as we do for the patients we serve.


If you believe you are the perfect match to join us on our pioneering adventure, then we invite you to apply and tell us more about your profile and motivation.

Job Segment: Biology, Medical Lab, Cell Biology, Biochemistry, Scientific, Science, Healthcare, Engineering

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