Senior Scientist - Molecular Biology Gene Therapy

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Date: Jul 30, 2019

Location: Boston, Massachusetts, US

Senior Scientist - Molecular Biology Gene Therapy

UCB New Medicines

Boston, MA


Help us transform patients’ lives.

At UCB, we put our heart, soul and skills into making a difference for people living with severe disease. Working together to push the boundaries, we blend the best of our talents to unlock innovation. Will you join us in our pioneering adventure?


Job Summary  

This position will serve as a driver of the molecular biology part of the gene therapy vector core being building to support AAV vector development, optimization and lead identification. The ideal candidate will have significant experience in molecular biology with preferably some experience in gene therapy.  This position will be based in the greater Boston area (Bedford MA).


Primary responsibilities :

  • Design and rapid execution of transgene design, testing, and optimization cycles including assessment of relevant biology in vitro/in vivo
  • Work closely with vector core members to ensure smooth transitions between groups with appropriate high-quality data packages generated
  • Drive projects locally with clear scientific direction and focus on critical path experiments, including providing scientific supervision as needed to more junior scientists and engaging with the broader team
  • Provide scientific insight and guidance in projects/platforms, including strong scientific thinking and hypothesis development, in collaboration with cross-functional teams at UCB (medicinal chemists, cell biologists, disease area exerts, antibody engineers, etc)

Education and experience:

  • PhD in applicable field with record of scientific achievement as evidenced by publications, presentations, or patents
  • 3+ years of experience in application of molecular biology
  • Experience of applying cellular and biochemical techniques in gene therapy preferred
  • Demonstrated experience in a matrixed drug discovery environment including working globally
  • Experience in molecular biology approaches and advanced cell biology techniques (flow cytometry, gene and protein analysis, PCR, cloning, viral work (AAV, lenti, adeno)
  • Excellent communicator, with demonstrated ability to work across disciplines
  • Ability to work independently, manage priorities, and engage in a multidisciplinary environment


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