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Scientist Upstream Process Science


Braine L'alleud, Walloon Brabant, Belgium

Job Function:  Process & Technology Development
Job ID:  64999

Help us transform patients' lives.

At UCB, we put our heart, soul, and skills into making a difference for people living with severe disease. Working together to push the boundaries, we blend the best of our talents to unlock innovation.  Will you join us in our pioneering adventure?

Scientist Upstream Process Science

UpStream Process Department 

Braine l’Alleud, Belgium  

Help us transform patients’ lives. 
At UCB, we put our heart, soul and skills into making a difference for people living with severe disease. Working together to push the boundaries, we blend the best of our talents to unlock innovation. Will you join us in our pioneering adventure? 

To strengthen our Biotech Sciences department, based in our hub in Braine l’Alleud, Belgium, we are looking to fill the position of: Scientist Upstream Process Science. 

Are you known for being empathetic with a driven twist? At UCB we see you as an ‘empathriven’ person. This incomparable blend of talent means you are adept at feeling for patient wellbeing and working on solutions with determination. 

As a UCB 'empathriven' person and Scientist Upstream Process Science you like to work in an environment where you can:

• Be involved in activities relating to the early stage process development and late stage process optimization, transfer and clinical/commercial manufacturing support for upstream processes to produce protein therapeutics with an emphasis on harvest and clarification step.

• Work in close collaboration with research, clinical and commercial manufacturing groups across the globe. You will work as part of virtual and matrix project teams across geographies and time zones. You will represent the Upstream Process Sciences group as appropriate in cross-functional project teams such as technical satellite teams responsible for the Chemistry, Manufacturing and Controls of specific recombinant proteins.

• Aid in harvest and clarification process development and optimization, process troubleshooting, investigations and characterization. You will coordinate and/or perform various upstream process development experiments as required, investigating culture conditions, product quality, filterability and upstream process scalability.

• Manage your own projects, diligently participate in the evaluation of products or technologies, and eventually author relevant sections of the regulatory submissions and external publications.  

• Execute the strategic directions of the Upstream Process Sciences group. 

As a UCB 'empathriven' person and Scientist Upstream Process Science you will contribute by: 
• Leading upstream process sciences projects in a matrix team, including guiding the design of experiments

• Coordinating experiment, pro-actively collecting feedback from team members and manage a team when applicable

• Applying Quality by Design (QbD) principles and Design of Experiment (DoE) methodology to design, plan and execute experiments

• Supervising and performing daily laboratory activities related to upstream process development, understanding, optimization, validation, transfers and scale up

• Providing expertise to troubleshoot upstream issues in the manufacturing environment

• Verifying data and analyzing results 
• Preparing and reviewing documentation (procedures, protocols, reports and potentially author relevant sections of the regulatory submissions and external publications as appropriate)

• Presenting / discussing results in project team meetings 
Interested? For this position you’ll need the following education, experience and skills: 
• Master’s degree or above, PhD degree preferred in Biology, Chemical Engineering or related discipline  

• 3-5 years of experience working with cell culture/fermentation, process development, preferably in a similar role in the biotech industry  

• Strong laboratory skills and a track record of spending >50% of current and past work function in the laboratory

• Proven experience leading projects in a matrix and virtual team and in a customer-oriented environment under deadlines

• An ability to multi-task, to organize and communicate large amounts of data is required

• High level of autonomy in the day to day work

• Must demonstrate flexibility and the ability to work in a team environment under deadlines 
• Good leadership and teambuilding skills

• Ability to multi-task, to organize and communicate large amounts of data

• Interpersonal skills to communicate and maintain good working relationships within the team and with internal/external partners

• Understanding of regulatory requirements and the importance of Health, Safety & Environment (HSE) as well as Quality policies and standards

• Ability to author and review comprehensive and accurate procedures, protocols and reports in English

• Good command of French is advisable

• Previous GMP experience is a plus 
To apply please go to www.ucb.com/careers.  
Discover more about the remarkable UCB Talent Blends and how you can contribute to the mix at www.ucb.com/careers


About us.

UCB- Inspired by Patients. Driven by Science. Everything we do starts with a simple question: “How will this create value for people living with severe diseases?” By putting patients at the heart of what we do, our approach – from discovery to development to delivery – is continuously transformed and designed around patient needs and their journey.

With a team of approximately 7,500 employees and operations in more than 40 countries, we are a global biopharmaceutical company investing more than a quarter of our revenue in cutting-edge scientific research. We are focused on addressing chronic, neurological, immunological, and bone diseases.

Curious to know more? Please visit our website www.ucb.com.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. 

Job Segment: Chemistry, Neurology, Scientific, Biotech, Immunology, Science, Engineering, Healthcare

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