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Let's push the boundaries together and make the most of your talents!

Senior Scientist CPRD

Location: 

Braine L'alleud, Walloon Brabant, Belgium

Job Function:  Process & Technology Development
Job ID:  64901

Senior Scientist, CPRD

 

Help us transform patients’ lives.

 

About UCB

 

At UCB, we put our heart, soul and skills into making a difference for people living with chronic diseases. Working together to push the boundaries, we blend the best of our talents to unlock innovation. Will you join us in our pioneering adventure?

Headquartered in Brussels, Belgium, UCB is a global biopharmaceutical company focused on the discovery and development of innovative medicines and solutions to transform the lives of people living with severe diseases of the immune system or of the central nervous system. UCB operates in approximately 40 countries, the company generated revenue of € 4.2 billion in 2016.


An opportunity has arisen for us to recruit a Senior Scientist (CPRD) within our Chemical Process and Development Department.

 

To strengthen our Pharmaceutical Sciences Department, we are looking to fill the position of Senior Scientist (CPRD).  

 

 

About the Role

 

Reporting to a Team Manager within CPRD, by applying cutting-edge scientific approaches, the applicant will develop safe, innovative and cost effective chemical processes for small molecule Active Pharmaceutical Ingredients (APIs). Primarily lab based, he/she will implement characterization methods (IPCs, PAT) to support process understanding and troubleshooting and will be intimately involved in the transfer of his/her processes to pilot plant and commercial manufacturing facilities

 

Major accountabilities

 

  • Developing safe, efficient, and cost effective chemical processes to support late-stage clinical trials and commercial manufacture of APIs.
  • Performing lab experiments (100 mg to multi-kg) to generate process understanding and deliverables (e.g. material, mass balance, fate of impurities…)
  • Transfer of process developed in the laboratory to pilot plant and/or commercial manufacturing facilities both at UCB and at partner organisations.
  • Troubleshooting of process/manufacturing issues, supported by labwork.
  • Literature searching to understand prior art and complete knowledge on experimental work.
  • Performing routine analyses independently (HPLC, GC, NMR…) to control processes, intermediates and final products.
  • Reporting results and conclusion (ELN, reports).
  • Reviewing technical documentation (batch records, specifications, reports from external partners).
  • Participation to the management of projects and working effectively within project teams.
  • Technical ownership and accountabilities of specific work packages (pilot plant, chemical step development, outsourced activities).

 

About You

 

  • For a PhD, ideally 2-5 years’ experience in a similar function in the pharmaceutical or fine chemical industry
  • For a Master, Minimum 3-8 years’ experience in the pharmaceutical industry.
  • Sound knowledge of organic chemistry and retrosynthesis.
  • Knowledge of the fundamentals of batch processing, unit operations and process safety.
  • Practical expertise in the laboratory, running a variety of transformations.
  • Good understanding of analytical techniques (NMR, HPLC, GC, mass spectrometry).
  • Computer literacy and knowledge of chemistry searching tools (Scifinder, Reaxys).
  • Desirable skills:
  • Practical experience at multi-kg scale.
  • Process Analytical Technologies (FBRM, PVM, ReactIR, Raman).
  • Knowledge of statistical tools, DoE principles, and kinetic studies (Dynochem).
  • Biotransformations.
  • Fluent in English, knowledge of French desirable.
  • Soft skills:
  • Ability to work within a  team, across a matrix organization.
  • Open to two-way feedback.
  • Passionate about chemistry and innovation.
  • Clear communication and presentation of results.

 

 

At UCB, growth and profitability constitute a guarantee for stability. You will always have the time and the backing needed to turn your ideas into reality. You can plan your future. 

 

We are building the next generation biopharma leader and need exceptional individuals to achieve this goal. We are looking for enthusiastic and talented professionals who thrive on challenge and change, and who want to make a difference and deliver results

 

At UCB human talent is the greatest asset of our organization – we continue to strengthen our talent pool, our organization and, our ability to deliver.  

Interested?

You can find out more about the organization at the company’s web site: www.ucb.com.  


Job Segment: Chemistry, Scientific, Chemical Research, Scientist, Pharmaceutical, Science, Engineering

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