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Let's push the boundaries together and make the most of your talents!

Scientist II - Computational Chemistry


Cambridge, Massachusetts, United States

Job Function:  Clinical Development
Job ID:  68824

Help us transform patients' lives.

At UCB, we put our heart, soul and skills into making a difference for people living with severe diseases.  Working together to push the boundaries, we blend the best of our talents to unlock innovation. Will you join us in this pioneering adventure? 





We’re seeking a Scientist II – Computational Chemist to join Ra Pharmaceuticals – UCB’s chemistry group as an integrated team member supporting small molecule and peptide drug discovery projects as well as the development of permeable peptide platforms. 


You like to work in an environment where you can:

  • Apply both structure and ligand based computational modeling methods to support all aspects of medicinal chemistry programs from hit to lead and lead optimization
  • Design and model cyclic peptide scaffold conformations for the development of large peptide libraries
  • Develop cheminformatics and bioinformatics tools to support hit deconvolution and hit follow-up efforts from the extreme diversity mRNA display and the permeable peptide platforms.


You will contribute by:

  • Leverage your computational chemistry experience by working with cross-functional teams in small molecule and peptide drug discovery
  • Develop your professional presence internally as a computational chemistry subject matter expert


Interested? For this position you’ll need the following education, experience and skills:

Minimum Qualifications:

  • Advanced degree in computational chemistry, computational biology, computational chemical biology, or related field; with 3+ years of industry experience as computational chemist.
  • Demonstrated strong track record of research accomplishment in computational chemistry; deep understanding of structural biology, MM and QM methods; and strong data analysis skills.
  • Mastery of computational software such as MOE, openeye, any MD simulation program and QM software.


Preferred Qualifications:

  • Familarity with Schrodinger, Pipeline pilot or KNIME, R and a scripting language are desired. Working knowledge with linux OS environment preferred.


Why you should apply

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees – just as we do for the patients we serve.
















About Us

At UCB, we come together every day to work, laser-focused, on a simple question: How will this create value for people living with severe diseases? By putting patients at the heart of everything we do, our approach – from discovery to development to delivery – is continuously transformed and designed around patient needs and their journey.

With a team of approximately 7,500 employees worldwide operations in more than 40 countries, we are a global biopharmaceutical company investing more than a quarter of our revenue in cutting-edge scientific research. We are focused on addressing chronic, neurological, immunological, and bone diseases. We are looking for people with passion and empathy who develop a real understanding of patient’s needs and can deliver thoughtful solutions to decisionmakers across the heath care ecosystem.

Curious to know more? Please visit our website www.ucb.com.


UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

Apply now »