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Principal Scientist - Senior Protein Purification Biochemist


Slough, Berkshire, United Kingdom

Job Function:  Research & Early Development
Job ID:  63775

Principal/Senior Scientist: Protein Purification Biochemist

UCB – Inspired by patients. Driven by science.

Help us transform patients’ lives.


Posting date: 16th August 2019

Application closing date: 16th September 2019

Location: Slough, UK

Salary: Competitive plus benefits.


About UCB


At UCB, we put our heart, soul and skills into making a difference for people living with severe diseases. We look to transform patients’ lives by pushing the boundaries of what is possible. With us, our talent makes the most of who they are, unlocking innovation and setting new standards for patients.


Everything we do starts with a simple question: “How will this make a difference to the lives of people living with severe diseases?” And to find the answers, we connect globally with patients and their families living with the physical and social burdens of severe disease. These connections give us new perspectives, drive our innovation, and offer a hope for a new generation of therapies that will help to transform lives.


To strengthen our Antibody Engineering Group, we are looking to fill the position of: Principal/Senior Scientist.


The Opportunity:

We are currently seeking a protein Biochemist with experience in antibody engineering and production to join a bispecific antibody engineering team. The role will focus on providing protein purification expertise and antibody engineering knowledge, to support the development of new antibody based therapeutic projects and technologies.


You will work as part of the team based at our world class research centre in Slough, UK.


About the Role

You will be responsible for:

  • Aiding the design of new antibody and protein therapeutics with manufacturing processing insights and confirming the suitability of these therapeutics for production.
  • Developing new antibody based therapeutic formats; including the development and implementation of new ideas and the support of therapeutic projects from conception to clinical development. 
  • Producing antibody and antibody like molecules; including their design, expression, purification and structural understanding. 
  • Incorporating detailed quality analysis into this work. 


About You

You should have:

  • PhD/MSc/BSc (or equivalent) with demonstrable experience in protein engineering and production.
  • Experience in manufacturing downstream processing design.
  • Good understanding of protein and antibody structure, engineering and production.
  • Practical experience in protein purification, protein analysis, and protein engineering.
  • You will be a flexible, team player with a drive to deliver; have good communication and presentation skills; and thrive in an exciting research environment.


UCB – The Facts

With more than 7500 employees in approximately 40 countries, we are a global biopharmaceutical company headquartered in Brussels, Belgium which invests in cutting-edge scientific research to meet unmet patient needs. A few other reasons that make UCB an amazing place to work:

  • Promising pipeline that includes several novel molecules and no major patent expiration in the next decade;
  • About 25% of 2016 revenue reinvested into Research & Development
  • 2018 Key Financials: €4.6 billion global revenue Specialties: Neurology, Immunology


Job Segment: Biochemistry, Neurology, Scientific, Immunology, Engineer, Engineering, Healthcare, Science

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